Publications

Explore selected publications from our team, highlighting their contributions to imaging science, clinical research, and innovation in ophthalmology.

Aqueous humour interleukin-6 and vision outcomes with anti-vascular endothelial growth factor therapy.

Sepah YJ, Do DV, Mesquida M, Day BM, Blotner S, Afridi R, Halim MS, Hong K, Wakshull E, Fauser S, Stoilov I, Dong Nguyen Q; HARBOR; READ-3 Investigators.
Eye (Lond). 2024 Jun;38(9):1755-1761. doi: 10.1038/s41433-024-03015-2. Epub 2024 Apr 15.

Macular Sensitivity Endpoints in Geographic Atrophy: Exploratory Analysis of Chroma and Spectri Clinical Trials.

Chang DS, Callaway NF, Steffen V, Csaky K, Guymer RH, Birch DG, Patel PJ, Ip M, Gao SS, Briggs J, Honigberg L, Lai P, Ferrara D, Sepah YJ.

Ophthalmol Sci. 2023 Jun 12;4(1):100351. doi: 10.1016/j.xops.2023.100351. eCollection 2024 Jan-Feb.

Optical coherence tomography angiography in diabetic retinopathy.

Waheed NK, Rosen RB, Jia Y, Munk MR, Huang D, Fawzi A, Chong V, Nguyen QD, Sepah Y, Pearce E.

Prog Retin Eye Res. 2023 Nov;97:101206. doi: 10.1016/j.preteyeres.2023.101206. Epub 2023 Jul 26.

ASSOCIATION OF ORAL MONTELUKAST WITH REDUCED ODDS OF DEVELOPING EXUDATIVE AGE-RELATED MACULAR DEGENERATION.

Matsumiya W, Karaca I, Pham BH, Akhavanrezayat A, Uludag G, Yasar C, Ghoraba H, Mobasserian A, Regenold J, Halim MS, Sepah YJ, Do DV, Chong V, Nguyen QD.

Retina. 2023 Nov 1;43(11):1914-1921. doi: 10.1097/IAE.0000000000003870.

Efficacy and Safety of Tocilizumab in the Management of Non-Infectious Uveitis Failed with Conventional Immunomodulatory and Anti-TNFα Therapies.

Uludag G, Karaca I, Akhavanrezayat A, Yasar C, Matsumiya W, Pham BH, Halim MS, Trong Tuong Than N, Sepah YJ, Do DV, Nguyen QD.

Ocul Immunol Inflamm. 2024 Aug;32(6):891-897. doi: 10.1080/09273948.2022.2126374. Epub 2022 Dec 21.

Longitudinal Comparative Analysis of Semi-Automated Aqueous Flare Measurements with Clinical Grading and Visual Outcomes in Uveitic Eyes.

Hasanreisoglu M, Halim MS, Kesim C, Doan HL, Tran ANT, Nguyen W, Besalti Z, Lajevardi S, Hassan M, Akhavanrezayat A, Ahmed MI, Do DV, Sepah YJ, Nguyen QD.

Ocul Immunol Inflamm. 2023 Nov;31(9):1819-1824. doi: 10.1080/09273948.2022.2123365. Epub 2022 Sep 28.

HORNBILL: a phase I/IIa trial examining the safety, tolerability and early response of BI 764524 in patients with diabetic retinopathy and diabetic macular ischaemia-rationale, study design and protocol.

Chong V, Nguyen QD, Sepah Y, Giani A, Pearce E.

Trials. 2022 Aug 17;23(1):669. doi: 10.1186/s13063-022-06527-y.

Corrigendum to Phase 1b Randomized Controlled Study of Short Course Topical Recombinant Human Nerve Growth Factor (rhNGF) for Neuroenhancement in Glaucoma: Safety, Tolerability, and Efficacy Measure Outcomes. Am J Ophthalmol 2022;234:223-234.

Beykin G, Stell L, Halim MS, Nuñez M, Popova L, Nguyen BT, Groth SL, Dennis A, Li Z, Atkins M, Khavari T, Wang SY, Chang R, Fisher AC, Sepah YJ, Goldberg JL.

Am J Ophthalmol. 2022 Oct;242:254. doi: 10.1016/j.ajo.2022.07.018. Epub 2022 Aug 14.

Proteomic analysis of autoimmune retinopathy implicates NrCAM as a potential biomarker.

Al-Moujahed A, Velez G, Vu JT, Lima de Carvalho JR, Levi SR, Bassuk AG, Sepah YJ, Tsang SH, Mahajan VB.

Ophthalmol Sci. 2022 Jun;2(2):100131. doi: 10.1016/j.xops.2022.100131. Epub 2022 Feb 24.

Two Phase 3 Studies on Ophthalmologic Effects of Roxadustat Versus Darbepoetin.

Sepah YJ, Nguyen QD, Yamaguchi Y, Otsuka T, Majikawa Y, Reusch M, Akizawa T.

Kidney Int Rep. 2022 Jan 19;7(4):763-775. doi: 10.1016/j.ekir.2022.01.1045. eCollection 2022 Apr.

Utilisation of composite endpoint outcome to assess efficacy of tocilizumab for non-infectious uveitis in the STOP-Uveitis Study.

Hassan M, Sadiq MA, Ormaechea MS, Uludağ G, Halim MS, Afridi R, Do DV, Sepah YJ, Nguyen QD.

Br J Ophthalmol. 2023 Aug;107(8):1197-1201. doi: 10.1136/bjophthalmol-2021-320604. Epub 2022 Apr 4.

Correlation of Clinical Aqueous Flare Grading to Semi-Automated Flare Measurements Using Laser Flare Photometry.

Halim MS, Hasanreisoglu M, Onghanseng N, Tran ANT, Hassan M, Yilmaz M, Segawa A, Gurelik G, Afridi R, Ormaechea MS, Uludag G, Kesim C, Nguyen NV, Bae JH, Park JH, Do DV, Ibrahim MA, Sepah YJ, Nguyen QD.

Ocul Immunol Inflamm. 2022 Oct-Nov;30(7-8):1906-1912. doi: 10.1080/09273948.2021.1971723. Epub 2022 Jan 26.

Evaluating optical coherence tomography (OCT) findings as potential biomarkers in central nervous system (CNS) lymphoma with or without ocular involvement.

Hassan M, Halim MS, Afridi R, Nguyen NV, Nguyen QD, Sepah YJ.

Int J Retina Vitreous. 2021 Nov 24;7(1):70. doi: 10.1186/s40942-021-00345-1.

Phase 1b Randomized Controlled Study of Short Course Topical Recombinant Human Nerve Growth Factor (rhNGF) for Neuroenhancement in Glaucoma: Safety, Tolerability, and Efficacy Measure Outcomes.

Beykin G, Stell L, Halim MS, Nuñez M, Popova L, Nguyen BT, Groth SL, Dennis A, Li Z, Atkins M, Khavari T, Wang SY, Chang R, Fisher AC, Sepah YJ, Goldberg JL.

Am J Ophthalmol. 2022 Feb;234:223-234. doi: 10.1016/j.ajo.2021.11.002. Epub 2021 Nov 13.

Effect of light backscattering from anterior segment structures on automated flare meter measurements.

Hasanreisoglu M, Kesim C, Yalinbas D, Yilmaz M, Uzunay NS, Aktas Z, Halim MS, Sepah YJ, Nguyen QD, Sahin A.

Eur J Ophthalmol. 2022 Jul;32(4):2291-2297. doi: 10.1177/11206721211039350. Epub 2021 Aug 12.

Distinct Patterns of Choroidal Lesions in Punctate Inner Choroidopathy and Multifocal Choroiditis Determined by Heatmap Analysis.

Park JG, Halim MS, Uludag G, Onghanseng N, Sredar N, Sepah YJ, Nguyen QD.

Ocul Immunol Inflamm. 2022 Feb 17;30(2):276-281. doi: 10.1080/09273948.2021.1939391. Epub 2021 Jul 6.

Current concepts in the diagnosis and management of antiphospholipid syndrome and ocular manifestations.

Uludag G, Onghanseng N, Tran ANT, Hassan M, Halim MS, Sepah YJ, Do DV, Nguyen QD.

J Ophthalmic Inflamm Infect. 2021 Apr 9;11(1):11. doi: 10.1186/s12348-021-00240-8.

Differences in the characteristics of subjects achieving complete, partial, or no resolution of macular edema in the READ-3 study.

Halim MS, Afridi R, Hasanreisoglu M, Hassan M, Ibrahim-Ahmed M, Do DV, Sepah YJ; READ-3 Investigators.

Graefes Arch Clin Exp Ophthalmol. 2021 Oct;259(10):2941-2948. doi: 10.1007/s00417-021-05148-6. Epub 2021 Apr 1.

Retraction Note to: Pharmacological agents in development for diabetic macular edema.

Sadiq MA, Halim MS, Hassan MM, Onghanseng N, Karaca I, Agarwal A, Afridi R, Sepah YJ, Do DV, Nguyen QD.

Int J Retina Vitreous. 2020 Dec 7;6(1):65. doi: 10.1186/s40942-020-00271-8.

Posterior segment inflammatory outcomes assessed using fluorescein angiography in the STOP-UVEITIS study.

Sadiq MA, Hassan M, Afridi R, Halim MS, Do DV, Sepah YJ, Nguyen QD; STOP-UVEITIS Investigators.

Int J Retina Vitreous. 2020 Oct 6;6:47. doi: 10.1186/s40942-020-00245-w. eCollection 2020.

Effect of Fundus Fluorescein Angiography on Semiautomated Aqueous Flare Measurements.

Halim MS, Onghanseng N, Park JH, Yilmaz M, Segawa A, Ertop M, Hassan M, Tran AN, Aktas Z, Ozdek S, Gurelik G, Do DV, Sepah YJ, Nguyen QD, Hasanreisoglu M.

Ocul Immunol Inflamm. 2022 Feb 17;30(2):424-427. doi: 10.1080/09273948.2020.1799036. Epub 2020 Sep 23.

Yet another case of ocular sarcoidosis.

Hien DL, Onghanseng N, Ngoc TTT, Hwang JJ, Pham BH, Doan HL, Nguyen HV, Halim MS, Uludag G, Sepah YJ, Do DV, Nguyen QD.

Am J Ophthalmol Case Rep. 2020 Jul 11;19:100825. doi: 10.1016/j.ajoc.2020.100825. eCollection 2020 Sep.

Pharmacological agents in development for diabetic macular edema.

Sadiq MA, Halim MS, Hassan M, Onghanseng N, Karaca I, Agarwal A, Afridi R, Sepah YJ, Do DV, Nguyen QD.

Int J Retina Vitreous. 2020 Jul 8;6:29. doi: 10.1186/s40942-020-00234-z. eCollection 2020.

Correction of perceived visual distortions using a software application and correlation to age-related macular degeneration.

Hassan M, Chakravarthy AD, Subramaniam M, Chundi P, Sadiq MA, Halim MS, Afridi R, Tran ANT, Sepah YJ, Do DV, Nguyen QD.

Ther Adv Ophthalmol. 2020 May 18;12:2515841420917783. doi: 10.1177/2515841420917783. eCollection 2020 Jan-Dec.

Eye trauma in falls presenting to the emergency department from 2006 through 2015.

Usmani B, Latif A, Iftikhar M, Sepah YJ, Parker C, Fliss JA, Dansingani KK, Shah SMA.

Br J Ophthalmol. 2021 Feb;105(2):198-204. doi: 10.1136/bjophthalmol-2019-314669. Epub 2020 Apr 23.

Severe vision loss secondary to retinal arteriolar occlusions after multiple intravitreal brolucizumab administrations.

Jain A, Chea S, Matsumiya W, Halim MS, Yaşar Ç, Kuang G, Sepah YJ, Khanani AM, Do DV, Nguyen QD.

Am J Ophthalmol Case Rep. 2020 Apr 2;18:100687. doi: 10.1016/j.ajoc.2020.100687. eCollection 2020 Jun.

Proteomic analysis of intermediate uveitis suggests myeloid cell recruitment and implicates IL-23 as a therapeutic target.

Sepah YJ, Velez G, Tang PH, Yang J, Chemudupati T, Li AS, Nguyen QD, Bassuk AG, Mahajan VB.

Am J Ophthalmol Case Rep. 2020 Mar 6;18:100646. doi: 10.1016/j.ajoc.2020.100646. eCollection 2020 Jun.

Retinal arterial occlusive vasculitis following intravitreal brolucizumab administration.

Haug SJ, Hien DL, Uludag G, Ngoc TTT, Lajevardi S, Halim MS, Sepah YJ, Do DV, Khanani AM.

Am J Ophthalmol Case Rep. 2020 Mar 31;18:100680. doi: 10.1016/j.ajoc.2020.100680. eCollection 2020 Jun.

Eye-Related Emergency Department Visits and The Opioid Epidemic: a 10-Year Analysis.

Usmani B, Latif A, Amarasekera S, Mukhtar S, Iftikhar M, Kherani S, Sepah YJ, Raghavan D, Smith WD, Jhanji V, Dansingani KK, Shah SMA.

Ophthalmic Epidemiol. 2020 Aug;27(4):300-309. doi: 10.1080/09286586.2020.1744165. Epub 2020 Mar 29.

Brolucizumab: Evolution through Preclinical and Clinical Studies and the Implications for the Management of Neovascular Age-Related Macular Degeneration.

Nguyen QD, Das A, Do DV, Dugel PU, Gomes A, Holz FG, Koh A, Pan CK, Sepah YJ, Patel N, MacLeod H, Maurer P.

Ophthalmology. 2020 Jul;127(7):963-976. doi: 10.1016/j.ophtha.2019.12.031. Epub 2020 Jan 17.

Comparison of montage with conventional stereoscopic seven-field photographs for assessment of ETDRS diabetic retinopathy severity.

Nguyen NV, Vigil EM, Hassan M, Halim MS, Baluyot SC, Guzman HA, Afridi R, Do DV, Sepah YJ.

Int J Retina Vitreous. 2019 Dec 13;5:51. doi: 10.1186/s40942-019-0201-z. eCollection 2019.

Topographic correlation between multifocal electroretinography, microperimetry, and spectral-domain optical coherence tomography of the macula in patients with birdshot chorioretinopathy.

Afridi R, Agarwal A, Nguyen NV, Hassan M, Sadiq MA, Nguyen QD, Sepah YJ.

J Ophthalmic Inflamm Infect. 2019 Dec 28;9(1):24. doi: 10.1186/s12348-019-0188-5.

Safety of systemic therapy for noninfectious uveitis.

Ormaechea MS, Hassan M, Onghanseng N, Park JH, Mahajan S, Al-Kirwi KY, Uludag G, Halim MS, Schlaen A, Sepah YJ, Do DV, Nguyen QD.

Expert Opin Drug Saf. 2019 Dec;18(12):1219-1235. doi: 10.1080/14740338.2019.1692810.

Comparison of Retinal Layer Thickness in Eyes with Resolved Diabetic Macular Edema Receiving Ranibizumab with Normal Eyes.

Rentiya ZS, Kherani S, Usmani B, Qazi MA, Sadiq MA, Iftikhar M, Nguyen QD, Shah SM, Sepah YJ; on behalf of the Read-3 study group.

Ophthalmologica. 2020;243(1):27-36. doi: 10.1159/000503326. Epub 2019 Nov 20.

Interleukin-6 inhibition in the management of non-infectious uveitis and beyond.

Karkhur S, Hasanreisoglu M, Vigil E, Halim MS, Hassan M, Plaza C, Nguyen NV, Afridi R, Tran AT, Do DV, Sepah YJ, Nguyen QD.

J Ophthalmic Inflamm Infect. 2019 Sep 16;9(1):17. doi: 10.1186/s12348-019-0182-y.

Primary outcomes of the VIDI study: phase 2, double-masked, randomized, active-controlled study of ASP8232 for diabetic macular edema.

Nguyen QD, Sepah YJ, Berger B, Brown D, Do DV, Garcia-Hernandez A, Patel S, Rahhal FM, Shildkrot Y, Renfurm RW; VIDI Research Group.

Int J Retina Vitreous. 2019 Aug 1;5:28. doi: 10.1186/s40942-019-0178-7. eCollection 2019.

Effect of vitreomacular adhesion on the treatment outcomes in the STOP-Uveitis clinical trial for non-infectious uveitis.

Hassan M, Nguyen NV, Halim MS, Afridi R, Sadiq MA, Karkhur S, Vigil E, Karabekirogullari S, Nguyen QD, Do DV, Sepah YJ; STOP-Uveitis Investigators.

J Ophthalmic Inflamm Infect. 2019 Jul 19;9(1):12. doi: 10.1186/s12348-019-0179-6.

Short-Term Effects of Ranibizumab on Diabetic Retinopathy Severity and Progression.

Hassan M, Sadiq MA, Halim MS, Afridi R, Nguyen NV, Sepah YJ.

Ophthalmol Retina. 2018 Jul;2(7):749-751. doi: 10.1016/j.oret.2018.02.008. Epub 2018 Mar 20.

New therapies in development for the management of non-infectious uveitis: A review.

Hassan M, Karkhur S, Bae JH, Halim MS, Ormaechea MS, Onghanseng N, Nguyen NV, Afridi R, Sepah YJ, Do DV, Nguyen QD.

Clin Exp Ophthalmol. 2019 Apr;47(3):396-417. doi: 10.1111/ceo.13511.

Alendronate induced chorioretinitis: The importance of meticulous assessments.

Hassan M, Maleki A, Ying Q, Nguyen N, Halim MS, Sepah YJ, Do DV, Nguyen QD.

Am J Ophthalmol Case Rep. 2019 Jan 9;14:21-25. doi: 10.1016/j.ajoc.2019.01.007. eCollection 2019 Jun.

Microperimetry for geographic atrophy secondary to age-related macular degeneration.

Csaky KG, Patel PJ, Sepah YJ, Birch DG, Do DV, Ip MS, Guymer RH, Luu CD, Gune S, Lin H, Ferrara D.

Surv Ophthalmol. 2019 May-Jun;64(3):353-364. doi: 10.1016/j.survophthal.2019.01.014. Epub 2019 Jan 28.

Blue light versus green light fundus autofluorescence in normal subjects and in patients with retinochoroidopathy secondary to retinal and uveitic diseases.

Bittencourt MG, Hassan M, Halim MS, Afridi R, Nguyen NV, Plaza C, Tran ANT, Ahmed MI, Nguyen QD, Sepah YJ.

J Ophthalmic Inflamm Infect. 2019 Jan 8;9(1):1. doi: 10.1186/s12348-018-0167-2.

Diurnal variation of choriocapillaris vessel flow density in normal subjects measured using optical coherence tomography angiography.

Sarwar S, Hassan M, Soliman MK, Halim MS, Sadiq MA, Afridi R, Agarwal A, Do DV, Nguyen QD, Sepah YJ.

Int J Retina Vitreous. 2018 Oct 10;4:37. doi: 10.1186/s40942-018-0140-0. eCollection 2018.

Intravitreal Sirolimus for the Treatment of Noninfectious Uveitis: Evolution through Preclinical and Clinical Studies.

Nguyen QD, Merrill PT, Sepah YJ, Ibrahim MA, Banker A, Leonardi A, Chernock M, Mudumba S, Do DV.

Ophthalmology. 2018 Dec;125(12):1984-1993. doi: 10.1016/j.ophtha.2018.06.015. Epub 2018 Jul 27.

Primary (Month-6) Outcomes of the STOP-Uveitis Study: Evaluating the Safety, Tolerability, and Efficacy of Tocilizumab in Patients With Noninfectious Uveitis.

Sepah YJ, Sadiq MA, Chu DS, Dacey M, Gallemore R, Dayani P, Hanout M, Hassan M, Afridi R, Agarwal A, Halim MS, Do DV, Nguyen QD.

Am J Ophthalmol. 2017 Nov;183:71-80. doi: 10.1016/j.ajo.2017.08.019. Epub 2017 Sep 5.

Evaluation of macular and peripapillary vessel flow density in eyes with no known pathology using optical coherence tomography angiography.

Hassan M, Sadiq MA, Halim MS, Afridi R, Soliman MK, Sarwar S, Agarwal A, Do DV, Nguyen QD, Sepah YJ.

Int J Retina Vitreous. 2017 Jul 31;3:27. doi: 10.1186/s40942-017-0080-0. eCollection 2017.

Corticosteroids as adjuvant therapy for ocular toxoplasmosis.

Jasper S, Vedula SS, John SS, Horo S, Sepah YJ, Nguyen QD.

Cochrane Database Syst Rev. 2017 Jan 26;1(1):CD007417. doi: 10.1002/14651858.CD007417.pub3.

Effects of Two Different Doses of Ranibizumab on Diabetic Retinopathy Severity.

Sadiq MA, Hassan M, Soliman MK, Afridi R, Do DV, Nguyen QD, Sepah YJ.

Ophthalmol Retina. 2017 Nov-Dec;1(6):566-567. doi: 10.1016/j.oret.2017.03.002. Epub 2017 May 10.

FLUOCINOLONE ACETONIDE IMPLANT FOR VOGT-KOYANAGI-HARADA DISEASE: Three-Year Outcomes of Efficacy and Safety.

Heo JW, Cho BJ, Goldstein DA, Sepah YJ, Do DV, Nguyen QD.

Retina. 2016 Nov;36(11):2124-2131. doi: 10.1097/IAE.0000000000001094.

Twenty-four-Month Outcomes of the Ranibizumab for Edema of the Macula in Diabetes – Protocol 3 with High Dose (READ-3) Study.

Sepah YJ, Sadiq MA, Boyer D, Callanan D, Gallemore R, Bennett M, Marcus D, Halperin L, Hassan M, Campochiaro PA, Nguyen QD, Do DV; READ-3 Study Group.

Ophthalmology. 2016 Dec;123(12):2581-2587. doi: 10.1016/j.ophtha.2016.08.040. Epub 2016 Oct 1.

Assessment of vitreous haze using ultra-wide field retinal imaging.

Dickson D, Agarwal A, Sadiq MA, Hassan M, High R, Nguyen QD, Sepah YJ.

J Ophthalmic Inflamm Infect. 2016 Dec;6(1):35. doi: 10.1186/s12348-016-0105-0. Epub 2016 Sep 29.

Subcutaneous repository corticotropin gel for non-infectious panuveitis: Reappraisal of an old pharmacologic agent.

Agarwal A, Hassan M, Sepah YJ, Do DV, Nguyen QD.

Am J Ophthalmol Case Rep. 2016 Sep 28;4:78-82. doi: 10.1016/j.ajoc.2016.09.004. eCollection 2016 Dec.

The Effect of Different Dosing Schedules of Intravitreal Sirolimus, a Mammalian Target of Rapamycin (mTOR) Inhibitor, in the Treatment of Non-Infectious Uveitis (An American Ophthalmological Society Thesis).

Nguyen QD, Sadiq MA, Soliman MK, Agarwal A, Do DV, Sepah YJ.

Trans Am Ophthalmol Soc. 2016 Aug;114:T3.

Retinal Vessel Caliber Measurement Using MultiColor and Infrared Confocal Scanning Laser Ophthalmoscopy Fundus Images.

Sarwar S, Hanout M, Sadiq MA, Soliman MK, Agarwal A, Do DV, Nguyen QD, Sepah YJ.

Int Ophthalmol Clin. 2016 Fall;56(4):67-83. doi: 10.1097/IIO.0000000000000142.

Correlation of Vitreomacular Traction with Foveal Thickness, Subfoveal Choroidal Thickness, and Vitreomacular/Foveal Angle.

Kozak I, Barteselli G, Sepah YJ, Sadiq MA, High R, Do DV, Nguyen QD.

Curr Eye Res. 2017 Feb;42(2):297-301. doi: 10.1080/02713683.2016.1175020. Epub 2016 Jun 30.

Spatial agreement between Goldmann visual field defects and fundus autofluorescence in patients with birdshot chorioretinopathy.

Jack LS, Agarwal A, Sepah YJ, Nguyen QD.

J Ophthalmic Inflamm Infect. 2016 Dec;6(1):18. doi: 10.1186/s12348-016-0085-0. Epub 2016 May 31.

SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY EVALUATION OF RETINAL STRUCTURE IN PATIENTS WITH SUSACS SYNDROME.

Agarwal A, Soliman M, Sarwar S, Sadiq MA, Do DV, Nguyen QD, Sepah YJ.

Retin Cases Brief Rep. 2017 Spring;11(2):123-125. doi: 10.1097/ICB.0000000000000308.

High-Resolution Imaging of Parafoveal Cones in Different Stages of Diabetic Retinopathy Using Adaptive Optics Fundus Camera.

Soliman MK, Sadiq MA, Agarwal A, Sarwar S, Hassan M, Hanout M, Graf F, High R, Do DV, Nguyen QD, Sepah YJ.

PLoS One. 2016 Apr 8;11(4):e0152788. doi: 10.1371/journal.pone.0152788. eCollection 2016.

The role of Aflibercept in the management of age-related macular degeneration.

Hassan M, Afridi R, Sadiq MA, Soliman MK, Agarwal A, Sepah YJ, Do DV, Nguyen QD.

Expert Opin Biol Ther. 2016;16(5):699-709. doi: 10.1517/14712598.2016.1167182.

Updates on the Clinical Trials in Diabetic Macular Edema.

Demirel S, Argo C, Agarwal A, Parriott J, Sepah YJ, Do DV, Nguyen QD.

Middle East Afr J Ophthalmol. 2016 Jan-Mar;23(1):3-12. doi: 10.4103/0974-9233.172293.

Aflibercept for neovascular age-related macular degeneration.

Sarwar S, Clearfield E, Soliman MK, Sadiq MA, Baldwin AJ, Hanout M, Agarwal A, Sepah YJ, Do DV, Nguyen QD.

Cochrane Database Syst Rev. 2016 Feb 8;2(2):CD011346. doi: 10.1002/14651858.CD011346.pub2.

Platelet derived growth factor inhibitors: A potential therapeutic approach for ocular neovascularization.

Sadiq MA, Hanout M, Sarwar S, Hassan M, Do DV, Nguyen QD, Sepah YJ.

Saudi J Ophthalmol. 2015 Oct-Dec;29(4):287-91. doi: 10.1016/j.sjopt.2015.05.005. Epub 2015 Jun 6.

Variation of choroidal thickness and vessel diameter in patients with posterior non-infectious uveitis.

Bittencourt MG, Kherani S, Ferraz DA, Ansari M, Nasir H, Sepah YJ, Hanout M, Do DV, Nguyen QD.

J Ophthalmic Inflamm Infect. 2014 Dec;4(1):14. doi: 10.1186/s12348-014-0014-z. Epub 2014 Aug 16.

Endogenous endophthalmitis: diagnosis, management, and prognosis.

Sadiq MA, Hassan M, Agarwal A, Sarwar S, Toufeeq S, Soliman MK, Hanout M, Sepah YJ, Do DV, Nguyen QD.

J Ophthalmic Inflamm Infect. 2015 Dec;5(1):32. doi: 10.1186/s12348-015-0063-y. Epub 2015 Nov 3.

Nonbiological pharmacotherapies for the treatment of diabetic macular edema.

Agarwal A, Parriott J, Demirel S, Argo C, Sepah YJ, Do DV, Nguyen QD.

Expert Opin Pharmacother. 2015;16(17):2625-35. doi: 10.1517/14656566.2015.1100172. Epub 2015 Nov 2.

Effect of Vitreomacular Adhesion on Treatment Outcomes in the Ranibizumab for Edema of the Macula in Diabetes (READ-3) Study.

Sadiq MA, Soliman MK, Sarwar S, Agarwal A, Hanout M, Demirel S, Rentiya ZS, Khan W, Do DV, Nguyen QD, Sepah YJ; READ-3 Study Group.

Ophthalmology. 2016 Feb;123(2):324-329. doi: 10.1016/j.ophtha.2015.09.032. Epub 2015 Oct 29.

Future Perspectives: Agents on the Horizon.

Maya JR, Sadiq MA, Agarwal A, Kaiser PK, Stoller GL, Sepah YJ, Nguyen QD.

Dev Ophthalmol. 2016;55:391-8. doi: 10.1159/000439037. Epub 2015 Oct 26.

Fusion Proteins: Aflibercept (VEGF Trap-Eye).

Sarwar S, Bakbak B, Sadiq MA, Sepah YJ, Shah SM, Ibrahim M, Do DV, Nguyen QD.

Dev Ophthalmol. 2016;55:282-94. doi: 10.1159/000439008. Epub 2015 Oct 26.

Platelet-Derived Growth Factor Inhibitors: A Potential Therapeutic Approach for Ocular Neovascularization.

Sadiq MA, Hanout M, Sarwar S, Hassan M, Agarwal A, Sepah YJ, Do DV, Nguyen QD.

Dev Ophthalmol. 2016;55:310-6. doi: 10.1159/000438953. Epub 2015 Oct 26.

Sirolimus for Retinal and Uveitic Diseases.

Agarwal A, Rajagopalan N, Hassan M, Sadiq MA, Soliman MK, Afridi R, Sepah YJ, Nguyen QD.

Dev Ophthalmol. 2016;55:276-81. doi: 10.1159/000438951. Epub 2015 Oct 26.

Structural Characteristics of Retinal Layers Adjacent to Geographic Atrophy.

Sadiq MA, Hanout M, Sarwar S, Rajagopalan N, Maya JR, Zapata LJ, Do DV, Nguyen QD, Sepah YJ.

Ophthalmic Surg Lasers Imaging Retina. 2015 Oct;46(9):914-9. doi: 10.3928/23258160-20151008-03.

Novel Therapies in Development for Diabetic Macular Edema.

Agarwal A, Afridi R, Hassan M, Sadiq MA, Sepah YJ, Do DV, Nguyen QD.

Curr Diab Rep. 2015 Oct;15(10):75. doi: 10.1007/s11892-015-0652-z.

Month-6 primary outcomes of the READ-3 study (Ranibizumab for Edema of the mAcula in Diabetes-Protocol 3 with high dose).

Do DV, Sepah YJ, Boyer D, Callanan D, Gallemore R, Bennett M, Marcus DM, Halperin L, Sadiq MA, Rajagopalan N, Campochiaro PA, Nguyen QD; READ-3 Study Group.

Eye (Lond). 2015 Dec;29(12):1538-44. doi: 10.1038/eye.2015.142. Epub 2015 Jul 31.

High-resolution adaptive optics findings in talc retinopathy.

Soliman MK, Sarwar S, Hanout M, Sadiq MA, Agarwal A, Gulati V, Nguyen QD, Sepah YJ.

Int J Retina Vitreous. 2015 Jul 24;1:10. doi: 10.1186/s40942-015-0009-4. eCollection 2015.

Adaptive Optics Imaging of Retinal Photoreceptors Overlying Lesions in White Dot Syndrome and its Functional Correlation.

Agarwal A, Soliman MK, Hanout M, Sadiq MA, Sarwar S, Jack LS, Do DV, Nguyen QD, Sepah YJ.Am J Ophthalmol. 2015 Oct;160(4):806-16.e2. doi: 10.1016/j.ajo.2015.07.013. Epub 2015 Jul 17.

Management of neovascular age-related macular degeneration: current state-of-the-art care for optimizing visual outcomes and therapies in development.

Agarwal A, Rhoades WR, Hanout M, Soliman MK, Sarwar S, Sadiq MA, Sepah YJ, Do DV, Nguyen QD.

Clin Ophthalmol. 2015 Jun 5;9:1001-15. doi: 10.2147/OPTH.S74959. eCollection 2015.

Assessment of changes in quality of life among patients in the SAVE Study – Sirolimus as therapeutic Approach to uVEitis: a randomized study to assess the safety and bioactivity of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis.

Vigil EM, Sepah YJ, Watters AL, Sadiq MA, Ansari M, Bittencourt MG, Ibrahim MA, Do DV, Nguyen QD.

J Ophthalmic Inflamm Infect. 2015 Apr 18;5:13. doi: 10.1186/s12348-015-0044-1. eCollection 2015.

Characterization of retinal structure and diagnosis of peripheral acquired retinoschisis using high-resolution ultrasound B-scan.

Agarwal A, Fan S, Invernizzi A, Do DV, Nguyen QD, Harms NV, Sepah YJ.

Graefes Arch Clin Exp Ophthalmol. 2016 Jan;254(1):69-75. doi: 10.1007/s00417-015-3013-3. Epub 2015 Apr 23.

What have we learnt about the management of diabetic macular edema in the antivascular endothelial growth factor and corticosteroid era?

Agarwal A, Sarwar S, Sepah YJ, Nguyen QD.

Curr Opin Ophthalmol. 2015 May;26(3):177-83. doi: 10.1097/ICU.0000000000000152.

One-Year Outcomes of the SAVE Study: Sirolimus as a Therapeutic Approach for UVEitis.

Ibrahim MA, Sepah YJ, Watters A, Bittencourt M, Vigil EM, Do DV, Nguyen QD.

Transl Vis Sci Technol. 2015 Mar 10;4(2):4. doi: 10.1167/tvst.4.2.4. eCollection 2015 Mar.

Fixation Stability Measurement Using Two Types of Microperimetry Devices.

Liu H, Bittencourt MG, Sophie R, Sepah YJ, Hanout M, Rentiya Z, Annam R, Scholl HP, Nguyen QD.

Transl Vis Sci Technol. 2015 Mar 10;4(2):3. doi: 10.1167/tvst.4.2.3. eCollection 2015 Mar.

Retinal sensitivity is a valuable complementary measurement to visual acuity–a microperimetry study in patients with maculopathies.

Liu H, Bittencourt MG, Wang J, Sepah YJ, Ibrahim-Ahmed M, Rentiya Z, Jang HS, Moradi A, Nguyen QD.

Graefes Arch Clin Exp Ophthalmol. 2015 Dec;253(12):2137-42. doi: 10.1007/s00417-015-2974-6. Epub 2015 Mar 7.

Assessment of oxygen saturation in retinal vessels of normal subjects and diabetic patients with and without retinopathy using Flow Oximetry System.

Ibrahim MA, Annam RE, Sepah YJ, Luu L, Bittencourt MG, Jang HS, Lemaillet P, Munoz B, Duncan DD, West S, Nguyen QD, Ramella-Roman JC.

Quant Imaging Med Surg. 2015 Feb;5(1):86-96. doi: 10.3978/j.issn.2223-4292.2014.11.26.

Diabetic retinopathy: variations in patient therapeutic outcomes and pharmacogenomics.

Agarwal A, Soliman MK, Sepah YJ, Do DV, Nguyen QD.Pharmgenomics Pers Med. 2014 Dec 12;7:399-409. doi: 10.2147/PGPM.S52821. eCollection 2014.

A randomized controlled trial of panretinal photocoagulation with and without intravitreal ranibizumab in treatment-naive eyes with non-high-risk proliferative diabetic retinopathy.

Ferraz DA, Vasquez LM, Preti RC, Motta A, Sophie R, Bittencourt MG, Sepah YJ, Monteiro ML, Nguyen QD, Takahashi WY.

Retina. 2015 Feb;35(2):280-7. doi: 10.1097/IAE.0000000000000363.

Assessment of Central Retinal Sensitivity Employing Two Types of Microperimetry Devices.

Liu H, Bittencourt MG, Wang J, Sophie R, Annam R, Ibrahim MA, Sepah YJ, Moradi A, Scholl HP, Nguyen QD.

Transl Vis Sci Technol. 2014 Sep 12;3(5):3. doi: 10.1167/tvst.3.5.3. eCollection 2014 Sep.

Diagnostic and therapeutic challenges.

Sadiq MA, Loh GK, Sepah YJ, Nguyen QD, Lin P.

Retina. 2015 Jun;35(6):1279-82. doi: 10.1097/IAE.0000000000000275.

Aspiration in injections: should we continue or abandon the practice?

Sepah Y, Samad L, Altaf A, Halim MS, Rajagopalan N, Javed Khan A.

F1000Res. 2014 Jul 10;3:157. doi: 10.12688/f1000research.1113.3. eCollection 2014.

Emerging therapies for noninfectious uveitis: what may be coming to the clinics.

Maya JR, Sadiq MA, Zapata LJ, Hanout M, Sarwar S, Rajagopalan N, Guinn KE, Sepah YJ, Nguyen QD.

J Ophthalmol. 2014;2014:310329. doi: 10.1155/2014/310329. Epub 2014 Apr 24.

Fundus autofluorescence imaging: Fundamentals and clinical relevance.

Sepah YJ, Akhtar A, Sadiq MA, Hafeez Y, Nasir H, Perez B, Mawji N, Dean DJ, Ferraz D, Nguyen QD.

Saudi J Ophthalmol. 2014 Apr;28(2):111-6. doi: 10.1016/j.sjopt.2014.03.008. Epub 2014 Mar 24.

Vascular endothelial growth factor trap-eye (Aflibercept) for the management of diabetic macular edema.

Moradi A, Sepah YJ, Sadiq MA, Nasir H, Kherani S, Sophie R, Do DV, Nguyen QD.

World J Diabetes. 2013 Dec 15;4(6):303-9. doi: 10.4239/wjd.v4.i6.303.

Therapies for neovascular age-related macular degeneration: current approaches and pharmacologic agents in development.

Hanout M, Ferraz D, Ansari M, Maqsood N, Kherani S, Sepah YJ, Rajagopalan N, Ibrahim M, Do DV, Nguyen QD.

Biomed Res Int. 2013;2013:830837. doi: 10.1155/2013/830837. Epub 2013 Nov 11.

Factors affecting visual outcomes in patients with diabetic macular edema treated with ranibizumab.

Channa R, Sophie R, Khwaja AA, Do DV, Hafiz G, Nguyen QD, Campochiaro PA; READ-2 Study Group.

Eye (Lond). 2014 Mar;28(3):269-78. doi: 10.1038/eye.2013.245. Epub 2013 Nov 22.

Management of retained subretinal perfluorocarbon liquid.

Shulman M, Sepah YJ, Chang S, Abrams GW, Do DV, Nguyen QD.

Ophthalmic Surg Lasers Imaging Retina. 2013 Nov 1;44(6):577-83. doi: 10.3928/23258160-20131105-07.

Cytologic features in vitreous preparations of patients with suspicion of intraocular lymphoma.

Rodriguez EF, Sepah YJ, Jang HS, Ibrahim M, Nguyen QD, Rodriguez FJ.

Diagn Cytopathol. 2014 Jan;42(1):37-44. doi: 10.1002/dc.23059. Epub 2013 Oct 25.

Retina-simulating phantom for optical coherence tomography.

Baxi J, Calhoun W, Sepah YJ, Hammer DX, Ilev I, Pfefer TJ, Nguyen QD, Agrawal A.

J Biomed Opt. 2014 Feb;19(2):21106. doi: 10.1117/1.JBO.19.2.021106.

Longitudinal spectral domain optical coherence tomography changes in eyes with intraocular lymphoma.

Jang HS, Sepah YJ, Sophie R, Bittencourt MG, Ferraz D, Hanout M, Liu H, Do DV, Nguyen QD.

J Ophthalmic Inflamm Infect. 2013 Sep 8;3(1):59. doi: 10.1186/1869-5760-3-59.

Corticosteroids as adjuvant therapy for ocular toxoplasmosis.

Jasper S, Vedula SS, John SS, Horo S, Sepah YJ, Nguyen QD.

Cochrane Database Syst Rev. 2013 Apr 30;4(4):CD007417. doi: 10.1002/14651858.CD007417.pub2.

Ranibizumab for edema of the macula in diabetes study: 3-year outcomes and the need for prolonged frequent treatment.

Do DV, Nguyen QD, Khwaja AA, Channa R, Sepah YJ, Sophie R, Hafiz G, Campochiaro PA; READ-2 Study Group.

JAMA Ophthalmol. 2013 Feb;131(2):139-45. doi: 10.1001/2013.jamaophthalmol.91.

In vivo identification of morphologic retinal abnormalities in neuromyelitis optica.

Sotirchos ES, Saidha S, Byraiah G, Mealy MA, Ibrahim MA, Sepah YJ, Newsome SD, Ratchford JN, Frohman EM, Balcer LJ, Crainiceanu CM, Nguyen QD, Levy M, Calabresi PA.

Neurology. 2013 Apr 9;80(15):1406-14. doi: 10.1212/WNL.0b013e31828c2f7a. Epub 2013 Mar 20.

Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE Study.

Nguyen QD, Ibrahim MA, Watters A, Bittencourt M, Yohannan J, Sepah YJ, Dunn JP, Naor J, Shams N, Shaikh O, Leder HA, Do DV.

J Ophthalmic Inflamm Infect. 2013 Feb 11;3(1):32. doi: 10.1186/1869-5760-3-32.

Ultra-wide-field retinal imaging in the management of non-infectious retinal vasculitis.

Leder HA, Campbell JP, Sepah YJ, Gan T, Dunn JP, Hatef E, Cho B, Ibrahim M, Bittencourt M, Channa R, Do DV, Nguyen QD.

J Ophthalmic Inflamm Infect. 2013 Feb 11;3(1):30. doi: 10.1186/1869-5760-3-30.

Association of retinal sensitivity to integrity of photoreceptor inner/outer segment junction in patients with diabetic macular edema.

Yohannan J, Bittencourt M, Sepah YJ, Hatef E, Sophie R, Moradi A, Liu H, Ibrahim M, Do DV, Coulantuoni E, Nguyen QD.

Ophthalmology. 2013 Jun;120(6):1254-61. doi: 10.1016/j.ophtha.2012.12.003. Epub 2013 Mar 15.

Diagnostic and therapeutic challenges.

Tauqir MZ, Shulman M, Bittencourt M, Sepah YJ, Ibrahim M, Do DV, Nguyen QD, Foster CS, Vora RA, Albini TA.

Retina. 2013 Apr;33(4):883-8. doi: 10.1097/IAE.0b013e31827b630b.

Vascular disrupting agent for neovascular age related macular degeneration: a pilot study of the safety and efficacy of intravenous combretastatin A-4 phosphate.

Ibrahim MA, Do DV, Sepah YJ, Shah SM, Van Anden E, Hafiz G, Donahue JK, Rivers R, Balkissoon J, Handa JT, Campochiaro PA, Nguyen QD.

BMC Pharmacol Toxicol. 2013 Jan 14;14:7. doi: 10.1186/2050-6511-14-7.

In vivo demonstration of homonymous hemimacular loss of retinal ganglion cells due to a thalamic lesion using optical coherence tomography.

Oh J, Sotirchos ES, Saidha S, Ibrahim M, Sepah Y, Nguyen QD, Calabresi PA.

JAMA Neurol. 2013 Mar 1;70(3):410-1. doi: 10.1001/jamaneurol.2013.605.

Reliability and reproducibility of spectral and time domain optical coherence tomography images before and after correction for patients with age-related macular degeneration.

Sadiq MA, Rashid A, Channa R, Hatef E, Do DV, Nguyen QD, Sepah YJ.

F1000Res. 2013 May 23;2:131. doi: 10.12688/f1000research.2-131.v2. eCollection 2013.

Choroidal neovascularization regression on fluorescein angiography after VEGF blockade.

Do DV, Greenwald L, Ibrahim M, Sepah Y, Nguyen QD.

Case Rep Ophthalmol. 2012 Sep;3(3):384-8. doi: 10.1159/000338969. Epub 2012 Nov 7.

Microcystic macular oedema, thickness of the inner nuclear layer of the retina, and disease characteristics in multiple sclerosis: a retrospective study.

Saidha S, Sotirchos ES, Ibrahim MA, Crainiceanu CM, Gelfand JM, Sepah YJ, Ratchford JN, Oh J, Seigo MA, Newsome SD, Balcer LJ, Frohman EM, Green AJ, Nguyen QD, Calabresi PA.

Lancet Neurol. 2012 Nov;11(11):963-72. doi: 10.1016/S1474-4422(12)70213-2. Epub 2012 Oct 4.

Wide-field retinal imaging in the management of noninfectious posterior uveitis.

Campbell JP, Leder HA, Sepah YJ, Gan T, Dunn JP, Hatef E, Cho B, Ibrahim M, Bittencourt M, Channa R, Do DV, Nguyen QD.

Am J Ophthalmol. 2012 Nov;154(5):908-911.e2. doi: 10.1016/j.ajo.2012.05.019. Epub 2012 Aug 28.

Comparison of time domain and spectral domain optical coherence tomography in measurement of macular thickness in macular edema secondary to diabetic retinopathy and retinal vein occlusion.

Hatef E, Khwaja A, Rentiya Z, Ibrahim M, Shulman M, Turkcuoglu P, Sepah Y, Wang J, Channa R, Bittencourt M, Akhtar A, Heo J, Do DV, Nguyen QD.

J Ophthalmol. 2012;2012:354783. doi: 10.1155/2012/354783. Epub 2012 Jul 25.

The role of biologic agents in the management of non-infectious uveitis.

Heo J, Sepah YJ, Yohannan J, Renner M, Akhtar A, Gregory A, Shulman M, Do DV, Nguyen QD.

Expert Opin Biol Ther. 2012 Aug;12(8):995-1008. doi: 10.1517/14712598.2012.688021.

New treatment options for noninfectious uveitis.

Gomes Bittencourt M, Sepah YJ, Do DV, Agbedia O, Akhtar A, Liu H, Akhlaq A, Annam R, Ibrahim M, Nguyen QD.

Dev Ophthalmol. 2012;51:134-61. doi: 10.1159/000336338. Epub 2012 Apr 17.

Sclerochoroidal calcifications imaged using enhanced depth imaging optical coherence tomography.

Yohannan J, Channa R, Dibernardo CW, Zimmer-Galler IE, Ibrahim M, Sepah YJ, Bittencourt M, Do DV, Nguyen QD.

Ocul Immunol Inflamm. 2012 Jun;20(3):190-2. doi: 10.3109/09273948.2012.670358. Epub 2012 Apr 9.

Retinal optical coherence tomography manifestations of intraocular lymphoma.

Liu TY, Ibrahim M, Bittencourt M, Sepah YJ, Do DV, Nguyen QD.

J Ophthalmic Inflamm Infect. 2012 Dec;2(4):215-8. doi: 10.1007/s12348-012-0072-z. Epub 2012 Apr 4.

Characterization of macular lesions in punctate inner choroidopathy with spectral domain optical coherence tomography.

Channa R, Ibrahim M, Sepah Y, Turkcuoglu P, Lee JH, Khwaja A, Hatef E, Bittencourt M, Heo J, Do DV, Nguyen QD.

J Ophthalmic Inflamm Infect. 2012 Sep;2(3):113-20. doi: 10.1007/s12348-011-0054-6. Epub 2012 Jan 1.

Aflibercept: a Potent Vascular Endothelial Growth Factor Antagonist for Neovascular Age-Related Macular Degeneration and Other Retinal Vascular Diseases.

Sophie R, Akhtar A, Sepah YJ, Ibrahim M, Bittencourt M, Do DV, Nguyen QD.

Biol Ther. 2012 May 29;2(1):3. doi: 10.1007/s13554-012-0003-4. eCollection 2012.